Perdomo had his contract selected by the Brewers on Friday.
The 28-year-old missed out on the Opening Day roster but will join the big-league club ahead of Friday's series opener in Atlanta. Perdomo sat out the 2021 campaign while recovering from Tommy John surgery and had a strong start to the season at Triple-A Nashville with a 2.25 ERA, 0.92 WHIP and 13:2 K:BB across 12 innings.