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Owners who are still competing in Week 17 will need to keep close tabs on which teams are resting starters before setting their Fantasy football picks. The Chiefs and Steelers have already announced they'll rest quarterbacks Patrick Mahomes and Ben Roethlisberger, which could be a major blow to owners who have ridden those superstars into title contention. Chad Henne and Mason Rudolph don't sky-high Fantasy appeal in relief, so who should you turn to in the Week 17 Fantasy football quarterback rankings?

Jaguars running back James Robinson was a waiver-wire MVP, but he'll also be out for the second week in a row with an ankle injury. Dare Ogunbowale looked steady in Week 16 with 71 yards on 14 carries, but Jacksonville is a 14-point underdog against the Colts in Week 17. Who can you trust as part of your Week 17 Fantasy football strategy? Before you lock in your lineups, be sure to check out the Week 17 Fantasy football rankings from the advanced computer model at SportsLine.

When it comes to ranking players, their model beat human experts in Fantasy football last season when there were big differences in ranking. Over the course of a season, that could literally be the difference between winning your league or going home empty-handed.

Last week, the model was extremely high on Bills wide receiver Stefon Diggs, saying he'd finish as a top-three player at his position. The result: Diggs recorded nine receptions for 145 yards and three touchdowns. Anybody who had him in their lineup was well on their way to a huge week.

Now, the model, which simulates every NFL game 10,000 times, has revealed its Fantasy football rankings for Week 17 of the 2020 NFL season. Head to SportsLine now to see them.

Top Fantasy football picks for Week 17

One player the model is extremely high on this week: Broncos running back Melvin Gordon. The two-time Pro Bowler's first season in Denver has been successful, as Gordon has rushed for 893 yards and eight touchdowns while adding 28 catches for 141 yards and another score. He's scored 56 times in the last five seasons and should be in line for plenty of touches in Week 17. 

Fellow running back Phillip Lindsay has been placed on injured reserve with knee and hip injuries, and Gordon has averaged 6.2 yards per carry over his last four games. The Broncos will take on a Raiders defense that has allowed at least 17 Fantasy points to running backs in three of their last four games. Las Vegas has also given up a total of 21 touchdowns to the position this season.

And a massive shocker: Cardinals quarterback Kyler Murray, who's accounted for 37 total touchdowns this season, stumbles big-time and doesn't even crack the top 15 at his position. 

Murray struggled mightily in Arizona's loss to the 49ers last week, throwing for 247 yards with one interception and no touchdowns. It was just the second time all season that the second-year signal caller failed to throw a touchdown pass. While Murray added 75 rushing yards on eight carries, his scrambling abilities could be hindered after suffering a lower leg injury against San Francisco. 

In addition, Murray and the Cardinals face off against the NFL's toughest defense this week. The Rams feature the NFL's top-ranked total defense, giving up just 286.5 yards per game this season. Los Angeles is also giving up just 192.3 passing yards per game, which also ranks first in the NFL. With such a tough matchup, Murray is a player to consider putting on the bench in Week 17.

How to set your Week 17 Fantasy football rankings

The model is also calling for a surprising quarterback you aren't even thinking about to finish in the top 10 of its Fantasy football rankings. This pick could be the difference between winning big and going home with nothing. You can see who it is here.

So who should you start and sit this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 17 Fantasy football rankings for every position, plus see which QB is going to come out of nowhere to crack the top 10, all from the model that out-performed experts big-time last season.