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Paredes was removed from Friday's game against the Cardinals due to leg tightness, Chandler Rome of The Athletic reports.
Paredes entered the game as a pinch hitter in the fourth inning but was later taken out of the game himself when his leg began to bother him in the eighth. If he ends up needing to sit out Saturday's contest as well, Nick Allen would presumably get the nod at shortstop.
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Astros' Isaac Paredes: Reinstated from bereavement list
Rotowire
The Astros activated Paredes (personal) from the bereavement list Monday.
Paredes was away for the weekend series against the Athletics but is back in time for the start of the Astros' three-game series in Colorado. He's out of the lineup Monday, and given the Astros' glut of infielders, Paredes faces an uncertain playing-time outlook. The 27-year-old is sporting a .227/.346/.409 batting line and 2:6 BB:K across his first 26 plate appearances this season.
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Astros' Isaac Paredes: Goes on bereavement list
Rotowire
The Astros placed Paredes on the bereavement list Friday, Matt Kawahara of the Houston Chronicle reports.
By rule, Paredes will miss at least the entire three-game weekend series against the Athletics and as many as four additional contests after that. Paredes has started six of seven games this season, but with Jeremy Pena getting back up to speed following a finger injury, Paredes' playing time could dip a bit once he's back from the bereavement list.
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Astros' Isaac Paredes: Out of Tuesday's lineup
Rotowire
Paredes is not in the lineup for Tuesday's game against the Red Sox.
Paredes started the first five games of the season across three different positions, and he'll hit the bench Tuesday after going 4-for-19 with two walks, three doubles, four RBI and three runs scored. Yordan Alvarez will serve as the designated hitter while Joey Loperfido receives a start in left field.
Paredes went 2-for-5 with two doubles, two RBI and a run scored during the Astros' 9-7 win over the Angels on Sunday.
Paredes gave the Astros an 8-6 lead with an two-run double in the eighth inning, which ended up being the winning runs for Houston. He went 0-for-7 with three strikeouts over the first two games of the series, but he turned things around over the final two contests, going 3-for-9 with one walk, four RBI and three runs scored. Paredes is looking to improve off his 2025 campaign, when he slashed .254/.352/.458 with 20 home runs and 53 RBI across 438 plate appearances.
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Astros' Isaac Paredes: In lineup again Friday
Rotowire
Paredes will bat third and DH in Friday's game against the Angels.
Paredes started at third base on Opening Day due to the absence of Jeremy Pena (finger), and even with Pena back in action, Paredes remains in the lineup. Houston will move Yordan Alvarez to left field to avoid a same-handed matchup between Joey Loperfido and Halos starter Yusei Kikuchi. While Paredes may not have an everyday role, he could force his way into the lineup if his bat gets hot.
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Astros' Isaac Paredes: Handling third base Opening Day
Rotowire
Paredes will start at third base and bat third in Thursday's opener versus the Angels.
Jeremy Pena (finger) is on the active roster but not quite ready to play yet, so Paredes will occupy the hot corner while Carlos Correa slides over to shortstop. When the Astros' roster is fully healthy, it's going to be more difficult for Paredes to find a regular spot in the lineup.
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