The Philadelphia Eagles have had the upper hand in their all-time series against the Atlanta Falcons, going 17-14-1 during the regular season while winning three of their four playoff meetings. Philadelphia has split its 16 regular-season games in Atlanta but hasn't fared well there of late, losing six of its last eight visits and each of the last three. The Eagles will attempt to end the skid when they visit the Falcons on Sunday in the 2021 NFL season-opener for both teams. Philadelphia and Atlanta both had dismal campaigns last year, recording only four victories and finishing last in their respective divisions.

Kickoff from Mercedes-Benz Stadium is set for 1 p.m. ET. Atlanta is a three-point favorite in the latest Eagles vs. Falcons odds from Caesars Sportsbook, while the over-under for total points scored is 48.5. Before locking in any Falcons vs. Eagles picks, make sure you check out the latest NFL predictions and analysis from SportsLine's proven projection model.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters the 2021 season on an incredible 120-78 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the Top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Eagles vs. Falcons on Sunday and just revealed its picks and predictions. You can visit SportsLine now to see the model's picks. Here are the NFL odds and betting trends for Falcons vs. Eagles:

  • Eagles vs. Falcons spread: Atlanta -3
  • Eagles vs. Falcons over-under: 48.5 points 
  • Eagles vs. Falcons money line: Philadelphia +150, Atlanta -175
  • PHI: Eagles are 0-6 against the spread in their last six road games 
  • ATL: Falcons are 0-5 ATS in their last five season-openers

Why the Falcons can cover

Atlanta endured its third consecutive losing season in 2020 but possessed one of the best passing offenses in the NFL, as it ranked fifth with an average of 272.7 yards through the air. Former MVP Matt Ryan finished fifth in the league with 4,581 passing yards, leaving him one away from tying Drew Brees (eight) for most 4,500-yard seasons in NFL history. The 36-year-old is ninth on the all-time list with 55,767 career yards and 10th with 347 touchdown tosses.

The Falcons haven't had a 1,000-yard rusher since Devonta Freeman in 2016, but they're hoping that changes this season. Atlanta signed Mike Davis to a two-year contract in March after the 28-year-old set career-highs of 642 yards and six touchdowns while filling in for the injured Christian McCaffrey as Carolina's feature back last year. Davis also contributed to the Panthers' passing game with personal bests of 59 catches, 373 receiving yards and two TDs.

Why the Eagles can cover

Carson Wentz fell short of expectations in Philadelphia and was shipped off to Indianapolis, clearing the way for Jalen Hurts to shoulder the responsibilities at quarterback. Selected in the second round of the 2020 NFL Draft, Hurts amassed 1,061 passing yards with six touchdowns and four interceptions in 15 games, including four starts. The 23-year-old played a major role in the Eagles' running game, as he gained 354 yards, which led all rookie signal-callers in the league.

Sirianni is hoping Hurts develops a relationship with DeVonta Smith, who was the 10th overall pick out of Alabama in this year's draft. The 22-year-old Smith became just the fourth wide receiver ever to win the Heisman Trophy in 2020 and first since Michigan's Desmond Howard in 1991. In helping the Crimson Tide to the national championship last year, Smith hauled in 117 passes for 1,856 yards and 23 touchdowns in 13 contests.

How to make Eagles vs. Falcons picks

SportsLine's model is leaning over on the point total. It says Ryan and Hurts combine to throw for more than three touchdowns. It also says one side of the spread cashes in well over 50 percent of simulations. You can only get the pick at SportsLine.

So who wins Eagles vs. Falcons on Sunday? And which side of the spread cashes well over 50 percent of the time? Visit SportsLine now to see which side of the Falcons vs. Eagles spread to be all over on Sunday, all from the advanced model that is up almost $7,900 on its top-rated NFL picks, and find out.