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The Buffalo Bills are back in action after their bye week and they head to Charlotte to take on a 4-3 Carolina Panthers team that's won three in a row and is 3-0 at home this season. Buffalo, meanwhile, started the year 4-0 but dropped games to the New England Patriots and Atlanta Falcons before the off week, so the Bills will certainly be looking to get back in the win column in Week 8.

You can't talk about the Bills without talking about star quarterback Josh Allen, the reigning MVP. Allen kicked off 2025 with seven touchdowns to one interception in the Bills' 4-0 start along with three rushing scores, but he had four touchdowns to three interceptions in the team's two losses. The Panthers, meanwhile, have scored at least 27 points in three of their last five games, and they survived a 13-6 affair with the winless New York Jets last week. Can Carolina get a signature win over one of the best teams in the NFL this weekend?

Before placing any bets of your own, check out our NFL betting guide. Our comprehensive guide gives out NFL betting tips, advice and strategies for all sorts of bet types, including NFL player props like anytime touchdown scorers. 

We'll be using DraftKings Sportsbook odds for anytime touchdown scorer props for Bills vs. Panthers. Here's the SportsLine Projection Model's game forecast Bills-Panthers, including more player props.

Top Bills vs. Panthers anytime touchdown scorer props:

Josh Allen (-105)

Allen is one of the toughest players to defend in general, but especially in the red zone. At 6-foot-5 and roughly 240 pounds, Allen is a tough runner who is incredibly mobile for his size. That's on full display near the goal line as he has 68 career rushing touchdowns to his name, including 30 since the start of 2023. Allen has found the end zone just once as a rusher since Week 1, but look for that to change this week as the Bills do whatever they can to snap a two-game losing streak.

Rico Dowdle (+135)

It's been a strange year for Dowdle, who began 2025 as the clear backup to Chuba Hubbard before exploding for 473 total yards in two games with Hubbard sidelined, both of which the Panthers won. Well, Hubbard returned to action last week and the two split carries. Hubbard rushed 13 times for 31 yards, while Dowdle was far more successful with 17 carries for 79 yards along with one 17-yard reception. It's clear Dowdle has the hot hand, and while splitting time relatively evenly between the two backs worked out well enough against a winless Jets team, the Bills are among the favorites to win the Super Bowl. The Panthers should use Dowdle more given he's the better back right now and Carolina's facing a great team. Even if it's another time share, Dowdle should have plenty of chances to find the end zone, either in short-yardage spots or with a long breakaway run.