Alabama vs. Mississippi State odds, line: 2022 college football picks, Week 8 predictions from proven model

SportsLine's model just revealed its college football picks for Mississippi State Bulldogs vs. Alabama Crimson Tide

By Scout Staff

Oct 22, 2022 at 4:30 pm ET • 3 min read

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The No. 6 Alabama Crimson Tide have no margin for error following their upset loss at Tennessee last week if they want to make the College Football Playoff. They cannot afford to lose another game during the regular season, which begins with a matchup against No. 24 Mississippi State on Saturday night. The Bulldogs are hoping to bounce back as well after losing a road game to Kentucky last week.

Kickoff is set for 7 p.m. ET. The Crimson Tide are 21-point favorites in the latest Alabama vs. Mississippi State odds from Caesars Sportsbook, while the over/under for total points scored is 61. Before entering any Mississippi State vs. Alabama picks, you'll want to see the college football predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Alabama vs. Mississippi State. You can head to SportsLine to see its picks. Here are several college football odds for Mississippi State vs. Alabama:

Alabama vs. Mississippi State spread: Alabama -21
Alabama vs. Mississippi State over/under: 61 points
Alabama vs. Mississippi State picks: See picks here

Why Alabama can cover

Alabama is in somewhat of a familiar position, as this will be the sixth time that the Crimson Tide have faced Mississippi State after a loss under head coach Nick Saban. They committed 17 penalties last week, causing them to drop out of the top five in the polls for the first time in 40 weeks. Saban has won 14 consecutive games against Mississippi State though, with only two of those contests being one-score games. The Crimson Tide have won each of the last four meetings by at least 24 points, including a 49-9 road win last season.

Mississippi State will be the only ranked team to travel to Tuscaloosa this season, giving Alabama another reason to be fully engaged on Saturday night. The Bulldogs have already struggled in a pair of conference road games, getting held to a combined 33 points in double-digit losses to LSU and Kentucky. They have only covered the spread once in their last seven games against Alabama, and the Crimson Tide have extra motivation on Saturday night.

Why Mississippi State can cover

Mississippi State was unable to capitalize on its offensive possessions last week, but it had scored at least 40 points in its previous three games. The Bulldogs put up 42 points against a talented Texas A&M defense before pouring in 40 points against Arkansas, so they are capable to scoring at a high rate again on Saturday. Junior quarterback Will Rogers is among the nation's leaders with 2,324 passing yards and 23 touchdowns.

Rogers has also taken care of the ball, throwing just four interceptions this season. Junior running back Dillon Johnson has rushed for 407 yards and three touchdowns, averaging 6.0 yards per carry.

How to make Alabama vs. Mississippi State picks

The model has simulated Mississippi State vs. Alabama 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread has all the value. You can only see the pick at SportsLine.

So who wins Alabama vs. Mississippi State? And which side of the spread has all the value? Visit SportsLine now to see which side of the Mississippi State vs. Alabama spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out.