Mitchell was activated from the reserve/COVID-19 list Saturday, Aaron Wilson of Sportstalk 790 Houston reports.
Mitchell's return will be a boost to the Texans' defense after he missed their Week 15 matchup with Jacksonville. The veteran has been a steady presence in the secondary, recording 52 tackles (39 solo), nine passes defensed, three forced fumbles and an interception in 12 games. He'll look to add to those numbers Sunday against the Chargers.