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The Oregon State Beavers will try to keep their late-season hot streak going on Saturday when they square off against the Loyola Chicago Ramblers in a 2021 NCAA Tournament Sweet 16 matchup at Bankers Life Fieldhouse in Indianapolis. The Beavers (19-12) are trying to win their sixth straight game. In two games in Indiana, they've knocked off No. 5 seed Tennessee and No. 4 seed Oklahoma State. Meanwhile the Ramblers (26-4) opened the tournament with a win over No. 9 seed Georgia Tech before knocking off No. 1 seed Illinois in the second round. The winner of Saturday's game will face either Houston or Syracuse for a berth in the Final Four. 

Tip-off is set for 2:40 p.m. ET on CBS. The Ramblers are favored by seven points in the latest Loyola Chicago vs. Oregon State odds from William Hill Sportsbook, while the over-under for total points scored is 125. Before making any Oregon State vs. Loyola Chicago picks, check out the March Madness college basketball predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Loyola vs. Oregon State in the NCAA Tournament 2021. You can head to SportsLine to see its picks. Here are several college basketball odds and trends for Oregon State vs. Loyola:

  • Loyola vs. Oregon State spread: Ramblers -7
  • Loyola vs. Oregon State over-under: 125 points
  • Loyola vs. Oregon State money line: Loyola -330, Oregon State +260
  • LOY: Team leads the country in defensive efficiency (86.1 points allowed per 100 possessions)
  • OSU: Team leads the Pac-12 in 3-point field goal percentage defense (30.1)

Why Loyola Chicago can cover 

After a four-game slump, Loyola's offense has come back to life. Since the start of the Missouri Valley Conference Tournament, the Ramblers are averaging 71.0 points a game and shooting 50.4 percent from the field and 45.7 percent from 3-point range. Prior to this hot streak, Loyola had managed just 57.3 points a game and shot 39.4 percent from the field and 25.0 percent from 3-point land in its previous four contests.

In addition, the Ramblers' defense is arguably the best in the nation. Loyola is limiting opponents to just 86.1 points per 100 possessions, which is the fewest in the country. The team has allowed more than 60 points only once since a 76-71 loss at Indiana State on Jan. 10 and has held opponents to 53.1 points a game and 30.4 percent shooting from beyond the 3-point arc in the last 20 outings.

Why Oregon State can cover

Oregon State has knocked off some quality teams during their five-game winning streak. In the Pac-12 Tournament, the Beavers beat UCLA, Oregon and Colorado en route to the title; the first two teams are still alive in the NCAA Tournament while the Buffaloes lost in the second round. Oregon State followed those wins with victories over Tennessee and Oklahoma State.

In addition, the Beavers have the bodies to contain Loyola big man Cameron Krutwig. Roman Silva (7-foot-1, 265), Maurice Calloo (6-foot-10, 220) and Dearon Tucker (6-foot-10, 240) have the height and size to bother Krutwig. In the victory over Oklahoma State, the three combined for 27 points and 18 rebounds while limiting Cowboys big man Kalib Boone to four points and zero rebounds.

How to make Oregon State vs. Loyola Chicago picks

The model is leaning over on the total, projecting the teams to combine for 135 points. It also says one side of the spread has all the value. You can only see the pick at SportsLine.

So who wins Oregon State vs. Loyola? And which side of the spread has all the value? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.