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The Oklahoma State Cowboys are seeking some payback Friday when they host the Kansas State Wildcats in a crucial Big 12 showdown. Kickoff is slated for 7:30 p.m. ET from Boone Pickens Stadium in Stillwater, Okla., in the nationally televised contest. Last year, the Wildcats got their first win in the series since 2018 with a 48-0 thumping of Oklahoma State (2-2, 0-1) that sent the Cowboys reeling, while the Wildcats (3-1, 1-0) went on to win the Big 12 title. Now, Oklahoma State needs to get back to its winning ways in an effort to salvage its hopes of a winning season and a potential bowl bid.

The Wildcats are 11.5-point favorites, and the over/under for total points scored is 53 in the latest Kansas State vs. Oklahoma State odds from the SportsLine consensus. Before locking in any Oklahoma State vs. Kansas State picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.

Now, the model has set its sights on Kansas State vs. Oklahoma State and just revealed its picks and predictions. You can visit SportsLine now to see the model's CFB picks. Here are several college football odds and trends for Oklahoma State vs. Kansas State:

  • Kansas State vs. Oklahoma State point spread: Kansas State -11.5
  • Kansas State vs. Oklahoma State over/under total: 53 points
  • Kansas State vs. Oklahoma State money line: Kansas State -453, Oklahoma State +344
  • KSU: The Wildcats are 7-3 against the spread in their past 10 games.
  • OSU: The Cowboys have won nine of the past 14 meetings in this series.
  • Kansas State vs. Oklahoma State picks: See picks at SportsLine
  • Kansas State vs. Oklahoma State live stream: fubo (try for free)

Why Kansas State can cover

In the win over UCF, Kansas State pulled away late in what had been a tight game behind an explosive running game that sparked a handful of long drives. In the process, the Wildcats might have found a new star running back in sophomore DJ Giddens, who ran for a career-high 207 yards and four touchdowns. Last year's Big 12 championship team was also fueled by an explosive running back, Deuce Vaughn, who is now with the Dallas Cowboys.

Giddens appeared shifty and elusive, appearing to gain more energy as the game wore on. His previous best performance was 15 carries for 128 yards in the opener against Southeast Missouri State. Kansas State coach Chris Klieman was quick to praise the development of Giddens following last week's game.

"We challenged him to step up and we were going to give him the football and keep giving it to him," Klieman said. See which team to pick here. 

Why Oklahoma State can cover

Oklahoma State coach Mike Gundy announced earlier this week that he is sticking with sixth-year senior Alan Bowman at quarterback, marking the first time this season Gundy has revealed his starting signal-caller before game day. Gundy told the media he thought the Cowboys had their most efficient all-around offensive performance in the loss to Iowa State. Although Bowman completed just 48% of his passes, he threw the ball away numerous times under heavy pressure to avoid sacks.

Bowman, who previously started at Texas Tech and spent time at Michigan, also made a couple big plays in the passing game that helped the Cowboys remain competitive. He threw a 60-yard touchdown pass to Jaden Nixon in the second quarter and added a 20-yard score to Rashod Owens in the fourth quarter. "He was able to function because we covered guys up in the running game, and we protected pretty well. I thought he played good enough to come back and get this start," Gundy said. See which team to pick here.

How to make Oklahoma State vs. Kansas State picks

SportsLine's model is leaning Under on the point total, projecting 46 combined points. The model also says one side of the spread hits well over 50% of the time. You can see the model's picks at SportsLine. 

So who wins Kansas State vs. Oklahoma State, and which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of more than $2,000 on its top-rated college football spread picks, and find out.