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1:37NFL Christmas Gifts: Gifting The No. 1 Seed In NFC
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3:37NFL Week 17 Picks: SNF Bears at 49ers
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1:21If Playoffs Started Today: No. 5 49ers at No. 4 Panthers
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1:53Colts Playoff Hopes Take a Hit With Loss Monday Night
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1:2349ers Roll Past Colts On Purdy's 5 TD Night
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1:07Are 49ers a Legit Threat To Win The NFC?
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3:0149ers and Colts Sound Off After San Francisco's Dominant Win On MNF
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1:18Philip Rivers Shows Improvements on Offense Despite Loss
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1:53Colts Defense Struggles as Their Playoff Hopes Sink
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2:30Week 16 Highlights: 49ers at Colts
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1:15Brock Purdy Picks Apart Colts For 5 TDs On MNF
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1:03This Just In: Brock Purdy Throws 9 TD's in Route To 11th Win
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1:36Seahawks 49ers Rams Fighting for NFC West Crown
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1:16MNF ATS Pick: 49ers at Colts O/U 46.5
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0:46MNF: 49ers at Colts Who Wins?
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1:0449ers Without WR Ricky Pearsall Tonight
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1:2349ers Still Alive For Top Seed In NFC & NFC West Crown
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1:53Bears Push Towards First NFC North Title Since 2018
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1:20Should More Faith Be Put In The 49ers Than The Seahawks?
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1:58Seahawks & 49ers Control Own Destiny For 1-Seed
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2025 Rushing
| STATS |
ATT
Rushing Attempts
|
YDS
Rushing Yards
|
AVG
Average Yards per Rush
|
TD
Rushing Touchdowns
|
LNG
Longest Rush
|
FL
Fumbles Lost
|
|---|---|---|---|---|---|---|
| Regular Season | — | — | — | — | — | — |
Top Isaac Guerendo News
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49ers' Isaac Guerendo: Inactive for MNF
Guerendo (coach's decision) is inactive for Monday night's game against the Colts.
Guerendo has appeared in all 14 games this season leading up to Monday night, but rookie Jordan James is getting the nod over him against the Colts as the Niners' RB3 behind Christian McCaffrey and Brian Robinson. All of Guerendo's 173 snaps this season have come on special teams.
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49ers' Isaac Guerendo: Role remains marginalized
Guerendo logged three snaps on special teams in Sunday's 37-24 win over the Titans.
Guerendo remained a non-factor on offense behind Christian McCaffrey and Brian Robinson on San Francisco's running back depth chart. The 25-year-old Guerendo once returned kickoffs for the 49ers, but the team has removed him from that role completely since Week 5. Barring a string of catastrophic injuries in the backfield, Guerendo can safely be ignored during the fantasy playoffs.
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49ers' Isaac Guerendo: No run on offense this season
Guerendo played all 10 of his snaps on special teams in Sunday's 26-15 loss to the Texans.
As a rookie last season, Guerendo showcased some explosiveness out of the San Francisco backfield with averages of 5.0 yards per carry and 10.1 yards per reception over 16 games, but he has yet to play a snap on offense in the 49ers' first eight games of 2025. With lead back Christian McCaffrey having thus far stayed healthy while handling huge snap and touch counts each week, Brian Robinson has picked up the remaining scraps left over in the backfield. So long as McCaffrey and Robinson are able to avoid injury, Guerendo looks as though he'll be limited to a role on kickoff returns and kick-coverage units.
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49ers' Isaac Guerendo: Returns one kickoff Thursday
Guerendo ran back one kickoff for 18 yards while receiving no carries or targets in Thursday's 26-23 overtime win over the Rams.
Christian McCaffrey continued to operate as San Francisco's bell cow (88 percent) while Brian Robinson (14 percent) remained the clear No. 2, which leaves Guerendo parked in the garage when the team is on offense. The 2024 fourth-round selection is stuck on special teams for the foreseeable future, needing an injury ahead of him on the depth chart to open up playing time. Guerendo generates no fantasy value in his current role when the 49ers visit the Buccaneers in Week 6.
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49ers' Isaac Guerendo: Logs 14 snaps on special teams
Guerendo logged 14 snaps on special teams and was not used on offense in Sunday's 26-21 loss to the Jaguars.
Guerendo couldn't even make an appearance in the box score as a return man after WR Skyy Moore handled all punt and kick returns Sunday. The 25-year-old Guerendo has logged zero snaps on offense through four games this season, leaving no room for fantasy utility as we encroach the quarter point of the season. Managers should have no concerns leaving Guerendo in the free-agent pool for Thursday's tilt against the Rams.
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49ers' Isaac Guerendo: Stuck on special teams
Guerendo did not receive a carry while gaining 19 yards on a kickoff return in Sunday's 16-15 win over the Cardinals.
Guerendo continued to be used exclusively on special teams, logging all 15 of his snaps there Sunday. Brian Robinson was the only running back to receive any carries outside of starter Christian McCaffrey. Guerendo carries no fantasy value heading into a Week 4 matchup against Jacksonville.
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49ers' Isaac Guerendo: No carries in Week 2 win
Guerendo returned two kickoffs for 47 yards and was not used on offense in Sunday's 26-21 win over the Saints.
Guerendo failed to see the field on offense Sunday, logging all 17 of his snaps on special teams. Veteran backup Brian Robinson continues to handle all of the touches starter Christian McCaffrey doesn't gobble up on game days. More of the same can be expected against the Cardinals in Week 3, leaving Guerendo off the fantasy radar until an injury opens up playing time for the sophomore.
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49ers' Isaac Guerendo: Limited to special teams
Guerendo played 15 snaps on special teams and did not receive a carry in Sunday's 17-13 win over the Seahawks.
The good news for Guerendo was that he was fully cleared from the shoulder injury that limited him in camp. The bad news for the sophomore tailback is that new addition Brian Robinson usurped him on the depth chart. Guerendo dropped to third in the pecking order and was limited to special teams, returning one kickoff for 16 yards. In his current role, Guerendo provides no fantasy utility heading into next Sunday's tilt against the Saints.
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Player Bio
| HT/WT: 6-0, 221 lbs |
| Birthplace: Clayton, IN |
| Age: 25 |
| School: Louisville |
| Experience: 2 |