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Karlaftis recorded 35 tackles (21 solo), including 8.0 sacks, and five passes defensed in 16 games during the regular season.

The defensive end added 13 tackles (nine solo), including 4.0 sacks, over Kansas City's three playoff games. Karlaftis finished with 10.5 sacks during the 2023 regular season and 6.0 as a rookie in 2022. The 2022 first-round pick also played on more than 700 defensive snaps in 2024 for the third year in a row.

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