NFL: New York Giants at Chicago Bears
Kena Krutsinger / USA TODAY Sports

The Carolina Panthers are riding high after winning each of their last three games. The Bears, meanwhile, have started the season 4-1 thanks in large part to an extremely stingy defense. Chicago enters Sunday's showdown against Carolina giving up just 20.0 points per game on defense this season, which ranks fourth in the NFL. Despite the loss of Christian McCaffrey early this season, Carolina enters Week 6 averaging 117.8 rushing yards per game. 

Kickoff for Bears vs. Panthers is set for 1 p.m. ET. Carolina is favored by one-point in the latest Panthers vs. Bears odds from William Hill, and the over-under is set at 45. Before entering any Bears vs. Panthers picks, you'll want to see the NFL predictions from the advanced computer model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception five-plus years ago. It's off to a strong 10-5 roll on top-rated picks this season. The model enters Week 6 on an incredible 106-70 run on top-rated NFL picks that dates back to the 2017 season. 

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Panthers vs. Bears. You can head to SportsLine to see its picks. Here are several NFL betting lines for Bears vs. Panthers:

  • Panthers vs. Bears spread: Panthers -1
  • Panthers vs. Bears over-under: 45 points
  • Panthers vs. Bears money line: Carolina -120, Chicago +100

Why the Panthers can cover

Running back Mike Davis has been sensational since taking over the starting role after McCaffrey (ankle) suffered an injury that has caused him to miss the majority of the season thus far. Davis enters Sunday's matchup against the Bears averaging 4.8 yards per carry this season. He's carried the ball 46 times for 220 yards and a touchdown. He's also recorded 30 receptions for 206 yards and two scores this season. 

Carolina's offense also features a plethora of weapons at the wide receiver position. Robby Anderson enters Week 6 with 489 receiving yards this season, which ranks fourth in the NFL. In Carolina's victory over the Falcons, Anderson caught eight of his 13 targets for 112 receiving yards. Fellow wideout D.J. Moore also had a big day against Atlanta, catching four passes for 93 yards and a touchdown. 

Why the Bears can cover

Chicago edged the Tampa Bay Buccaneers last Thursday, 20-19. Cairo Santos kicked a 38-yard field goal with 1:17 remaining to earn the victory. DeAndre Houston-Carson broke up Tom Brady's fourth-down pass with 33 seconds left to preserve the win. Chicago overcame an early 13-0 deficit with two touchdowns in the final 1:48 of the first half. David Montgomery rushed for a 3-yard TD, then Robert Quinn forced a fumble that led to a 12-yard TD reception by Jimmy Graham

Khalil Mack had two sacks, matching his highest sack total since a Week 3 win at Washington last season. He ended a 17-game streak without two or more sacks. Allen Robinson led the team and tied a career-high with 10 receptions for 90 yards in Week 5, his fifth career game with 10 catches. The Bears have won four of the last five meetings with the Panthers and six of nine overall. 

How to make Bears vs. Panthers picks

The model has simulated Panthers vs. Bears 10,000 times and the results are in. It is leaning over on the total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Panthers vs. Bears? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the Bears vs. Panthers spread to jump on Sunday, all from the model that enters Week 6 of the NFL season on an incredible 106-70 roll.