49ers' Nick Bosa: Held out of Wednesday's practice

Bosa (hamstring) didn't practice Wednesday, Eric Branch of the San Francisco Chronicle reports.

Bosa opened Week 14 prep as a spectator during Wednesday's session, after head coach Kyle Shanahan previously said the star pass rusher is dealing with a "hamstring irritation" that the team will work through, per David Lombardi of The Athletic. Though the 25-year-old collected a season-high three sacks and forced a fumble on just 38 defensive snaps last weekend versus Miami, his status is definitely worth monitoring as the week goes on.