NFL odds, picks, predictions for Week 2: Advanced computer model loving Ravens, Patriots

The Week 2 NFL odds continue to shift as NFL news breaks. Even after their Week 1 face-plant against the Titans, the Browns are now 6.5-point favorites against the Jets on Monday Night Football, up four points from the opening line. Quarterback Sam Darnold (mono) has been ruled out for that game, while running back Le'Veon Bell (shoulder) is questionable. The over-under for that matchup now sits at 44.5, down two points from the opening line, while the game boasts one of the larger NFL spreads of the week. Meanwhile, the Cowboys (-5.5) have also seen their line against the Redskins rise a point as running back Derrius Guice (knee) has been ruled out for Washington. Instead, the team will turn to veteran Adrian Peterson, who rushed for over 1,000 yards last season. With NFL lines on the move all the way up to kickoff, be sure to see the top Week 2 NFL picks from the proven model at SportsLine. It'll help you make optimal NFL predictions this week.

The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It has nailed its recent top-rated NFL picks, entering Week 2 of the 2019 NFL season on a sizzling 17-6 run that dates back to last season. It's also on a strong 79-49 roll on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the top 10 on for the third straight year on straight-up NFL picks and beat over 96 percent of CBS Sports office pool players. Anyone who has followed it is way up

Now, it has examined the latest Week 2 NFL odds and lines, simulated every snap, and its football predictions are in. One of the top Week 2 NFL predictions the model recommends: the Patriots (-19) cover the largest spread of Week 2 in a win over the Dolphins at Hard Rock Stadium, avenging their stunning 34-33 loss to Miami last December. 

The Patriots surged to the top of the 2020 Super Bowl odds with a dominant 33-3 win over the Steelers in Week 1. And they'll only get stronger with the addition of wide receiver Antonio Brown, who is set to play in Week 2. The Dolphins, meanwhile, looked like perhaps the worst team in the NFL in a 59-10 loss to the Ravens in Week 1. The Pats cover the spread in well over 50 percent of simulations, according to the model, while there's also value on the Over (48.5) because the model is projecting 49 total points. 

Another one of the Week 2 NFL picks from the model: the Ravens cover as 13-point home favorites against the Cardinals in a 1 p.m. ET kickoff from M&T Bank Stadium. 

Despite rebuilding their defense during the offseason, the Ravens made a statement in Week 1, blasting the Miami Dolphins 59-10 in a game that was never in doubt. They covered the spread (-7) with a whopping 42 points to spare.

The new-look defense was impressive, but it was the passing attack that turned heads. Quarterback Lamar Jackson had all day to throw and picked apart Miami, completing 17-of-20 passes for 324 yards and five touchdowns. Rookie receiver Marquise Brown was a breakout star, putting up an impressive 4-147-2 line.

Rookie quarterback Kyler Murray, meanwhile, led an impressive comeback for Arizona that led to a tie against Detroit. SportsLine's model, however, is calling for under 200 yards of total offense for the No. 1 overall pick in the 2019 NFL Draft as Baltimore's defense keeps him under wraps. The Ravens cover the two-score spread in well over 50 percent of simulations, while the under (46.5) is the best play on the total because that hits more than half the time as well. 

The model also has a strong pick for Eagles vs. Falcons on Sunday Night Football, and is calling for a Super Bowl contender to go down hard this week. You can only get every pick for every game at SportsLine.

What NFL picks can you make with confidence in Week 2? And which Super Bowl contender goes down hard? Check out the latest NFL odds below and then visit SportsLine to see which NFL teams are winning more than 50 percent of simulations, all from the model that is up over $7,000 on its top-rated NFL picks

Indianapolis Colts at Tennessee Titans (-3, 44)
Los Angeles Chargers at Detroit Lions (+1.5, 47)
Buffalo Bills at New York Giants (+2, 44.5)
Arizona Cardinals at Baltimore Ravens (-13, 46.5)
New England Patriots at Miami Dolphins (+19, 48.5)
Dallas Cowboys at Washington Redskins (+5.5, 46.5)
Jacksonville Jaguars at Houston Texans (-8.5, 43)
Seattle Seahawks at Pittsburgh Steelers (-3.5, 47)
San Francisco 49ers at Cincinnati Bengals (-1, 46)
Minnesota Vikings at Green Bay Packers (-2.5, 43)
Kansas City Chiefs at Oakland Raiders (+7, 53.5)
New Orleans Saints at Los Angeles Rams (-2, 52)
Chicago Bears at Denver Broncos (+2.5, 40)
Philadelphia Eagles at Atlanta Falcons (+1.5, 52.5)
Cleveland Browns at New York Jets (+6.5, 44.5)

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