Alabama vs. Oklahoma prediction, odds: 2025 College Football Playoff first round picks by proven model
The SportsLine Projection Model has revealed its Alabama Crimson Tide vs. Oklahoma Sooners picks for Saturday's 2025 College Football Playoff first-round matchup

A pair of Southeastern Conference powers meet when the ninth-ranked Alabama Crimson Tide battle the eighth-ranked Oklahoma Sooners in a College Football Playoff first-round matchup on Friday. Alabama is coming off a 28-7 loss to Georgia in the SEC Championship Game on Dec. 6, while Oklahoma finished with a 17-13 win over LSU on Nov. 29. The Crimson Tide (10-3), who were tied atop the SEC regular season standings at 7-1, are 4-2 against ranked opponents this season. The Sooners (10-2), who tied for fifth in the conference at 6-2, are 5-1 against ranked foes.
Kickoff from Gaylord Family Oklahoma Memorial Stadium in Norman, Okla., is at 8 p.m. ET. OU leads the all-time series 5-1, including a 23-21 win on Nov. 15. The Sooners are 1.5-point favorites in the latest Oklahoma vs. Alabama odds, while the over/under for total points scored is 41.5 via SportsLine consensus. Before making any Alabama vs. Oklahoma picks, check out the college football predictions from the SportsLine Projection Model.
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The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season. Anybody following those college football betting picks at sportsbooks and on betting sites could have seen strong returns.
Now, the model has set its sights on Alabama vs. Oklahoma. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for Oklahoma vs. Alabama:
Alabama vs. Oklahoma spread | Oklahoma -1.5 at DraftKings Sportsbook |
Alabama vs. Oklahoma over/under | 41.5 points |
Alabama vs. Oklahoma money line | Alabama -104, Oklahoma -115 |
Alabama vs. Oklahoma picks | |
Alabama vs. Oklahoma streaming | Fubo (Try for free) |
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Why Alabama can cover
Junior quarterback Ty Simpson helps power the Crimson Tide offense. In 13 games, he has completed 64.3% of his passes for 3,268 yards and 26 touchdowns with five interceptions and a 146.1 rating. He has also rushed for two scores. In the loss to the Sooners, he completed 28 of 42 passes for 326 yards and one touchdown with one interception. In a 38-14 win over Wisconsin on Sept. 13, he completed 24 of 29 passes for 382 yards and four touchdowns.
His top target is senior wide receiver Germie Bernard. In 12 games, he has 57 receptions for 762 yards (13.4 average) and seven touchdowns. He has also rushed 17 times for 101 yards and two touchdowns. In the loss to Georgia, he caught six passes for 62 yards and one touchdown. He had five catches for 54 yards and a score in a 29-22 win over South Carolina on Oct. 25. See which team to back at SportsLine.
Why Oklahoma can cover
Junior quarterback John Mateer leads the Sooners' attack. In 11 games, he has completed 62.1% of his passes for 2,578 yards and 12 touchdowns with 10 interceptions and a 128.4 rating. He has also rushed 130 times for 416 yards (3.2 average) and seven touchdowns. In the win over LSU, he completed 23 of 38 yards for 318 yards and two touchdowns with three interceptions.
Junior wide receiver Isaiah Sategna III is Oklahoma's top receiver. In 12 games, he has 65 receptions for 948 yards (14.6 average) and seven touchdowns. In the win over LSU, he caught nine passes for 121 yards and one touchdown. He had three receptions for 109 yards and one score in a 17-6 win over Missouri on Nov. 22. See which team to back at SportsLine.
How to make Oklahoma vs. Alabama picks
SportsLine's model has simulated Alabama vs. Oklahoma 10,000 times and is going Over on the total. It also says one side of the spread has all of the value. You can see the model's pick at SportsLine.
So who wins Oklahoma vs. Alabama, and which side of the spread is the better value? Visit SportsLine now to see which side of the Alabama vs. Oklahoma spread to jump on, all from the advanced model that's up on its top-ranked money-line and total picks, and find out.
















