Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | D. Brees Drew Brees | T. Bridgewater Teddy Bridgewater | |
| Running Back | A. Kamara Alvin Kamara | M. Ingram Mark Ingram | |
| Fullback | Z. Line Zach Line | — | — |
| Wide Receiver | M. Thomas Michael Thomas | T. Smith Tre'Quan Smith | |
| Tight End | B. Watson Benjamin Watson | J. Hill Josh Hill | |
| Left Tackle | T. Armstead Terron Armstead | J. Bushrod Jermon Bushrod | — |
| Left Guard | A. Peat Andrus Peat | C. Green Chaz Green | — |
| Center | M. Unger Max Unger | C. Tom Cameron Tom | |
| Right Guard | L. Warford Larry Warford | — | — |
| Right Tackle | R. Ramczyk Ryan Ramczyk | M. Ola Michael Ola | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | C. Jordan Cameron Jordan | T. Hendrickson Trey Hendrickson | |
| Right Defensive Tackle | T. Davison Tyeler Davison | T. Stallworth Taylor Stallworth | — |
| Left Defensive Tackle | S. Rankins Sheldon Rankins | D. Onyemata David Onyemata | |
| Strongside Linebacker | A. Klein A.J. Klein | — | — |
| Middle Linebacker | M. Te'o Manti Te'o | — | — |
| Weakside Linebacker | D. Davis Demario Davis | A. Anzalone Alex Anzalone | |
| Right Cornerback | M. Lattimore Marshon Lattimore | P. Williams P.J. Williams | |
| Left Cornerback | E. Apple Eli Apple | J. Hardee Justin Hardee | |
| Strong Safety | V. Bell Vonn Bell | K. Coleman Kurt Coleman | — |
| Free Safety | M. Williams Marcus Williams | C. Banjo Chris Banjo |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | T. Morstead Thomas Morstead | — | — |
| Kicker | W. Lutz Wil Lutz | — | — |
| Long Snapper | Z. Wood Zach Wood | J. Hill Josh Hill | — |
| Holder | T. Morstead Thomas Morstead | — | — |
| Punt Returner | A. Carr Austin Carr | A. Kamara Alvin Kamara | — |
| Kick Returner | T. Hill Taysom Hill | — | — |