Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | B. MayfieldBaker Mayfield | T. BridgewaterTeddy Bridgewater | |
| Running Back | B. IrvingBucky Irving | R. WhiteRachaad White | |
| Wide Receiver | M. EvansMike Evans | E. EgbukaEmeka Egbuka | |
| Tight End | C. OttonCade Otton | P. DurhamPayne Durham | |
| Left Tackle | T. WirfsTristan Wirfs | B. ChukwumaBen Chukwuma | |
| Left Guard | M. JordanMike Jordan | E. KleinElijah Klein | |
| Center | G. BartonGraham Barton | B. BredesonBen Bredeson | — |
| Right Guard | D. FeeneyDan Feeney | L. HaggardLuke Haggard | |
| Right Tackle | L. GoedekeLuke Goedeke | C. HeckCharlie Heck |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | E. RobertsElijah Roberts | G. BartonGraham Barton | |
| Nose Tackle | V. VeaVita Vea | E. SimmonsElijah Simmons | — |
| Right Defensive End | L. HallLogan Hall | G. GainesGreg Gaines | — |
| Left Inside Linebacker | S. DennisSirVocea Dennis | D. JonesDeion Jones | |
| Right Inside Linebacker | L. DavidLavonte David | A. WalkerAnthony Walker | — |
| Strongside Linebacker | H. ReddickHaason Reddick | A. NelsonAnthony Nelson | |
| Weakside Linebacker | Y. DiabyYaYa Diaby | C. BraswellChris Braswell | |
| Right Cornerback | B. MorrisonBenjamin Morrison | K. VildorKindle Vildor | |
| Left Cornerback | J. DeanJamel Dean | J. HayesJosh Hayes | — |
| Slot Cornerback | J. ParrishJacob Parrish | — | — |
| Strong Safety | A. Winfield Jr.Antoine Winfield Jr. | C. IzienChristian Izien | — |
| Free Safety | T. SmithTykee Smith | R. WisdomRashad Wisdom |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | R. DixonRiley Dixon | — | — |
| Kicker | C. McLaughlinChase McLaughlin | — | — |
| Long Snapper | E. DeckersEvan Deckers | — | — |
| Holder | R. DixonRiley Dixon | — | — |
| Punt Returner | K. JohnsonKameron Johnson | T. JohnsonTez Johnson | |
| Kick Returner | K. JohnsonKameron Johnson | S. TuckerSean Tucker |