Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | M. Trubisky Mitchell Trubisky | N. Foles Nick Foles | — |
| Running Back | D. Montgomery David Montgomery | T. Cohen Tarik Cohen | |
| Wide Receiver | A. Robinson Allen Robinson | D. Mooney Darnell Mooney | |
| Tight End | J. Graham Jimmy Graham | C. Kmet Cole Kmet | |
| Left Tackle | C. Leno Jr. Charles Leno Jr. | A. Bars Alex Bars | — |
| Left Guard | J. Daniels James Daniels | A. Hambright Arlington Hambright | — |
| Center | C. Whitehair Cody Whitehair | — | — |
| Right Guard | G. Ifedi Germain Ifedi | R. Coward Rashaad Coward | — |
| Right Tackle | B. Massie Bobby Massie | J. Spriggs Jason Spriggs | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | A. Hicks Akiem Hicks | B. Urban Brent Urban | — |
| Nose Tackle | B. Nichols Bilal Nichols | J. Jenkins John Jenkins | — |
| Right Defensive End | R. Robertson-Harris Roy Robertson-Harris | M. Edwards Mario Edwards | — |
| Left Inside Linebacker | R. Smith Roquan Smith | J. Woods Josh Woods | — |
| Right Inside Linebacker | D. Trevathan Danny Trevathan | J. Iyiegbuniwe Joel Iyiegbuniwe | — |
| Strongside Linebacker | R. Quinn Robert Quinn | B. Mingo Barkevious Mingo | |
| Weakside Linebacker | K. Mack Khalil Mack | T. Gipson Trevis Gipson | — |
| Right Cornerback | K. Fuller Kyle Fuller | B. Skrine Buster Skrine | |
| Left Cornerback | J. Johnson Jaylon Johnson | K. Vildor Kindle Vildor | |
| Strong Safety | T. Gipson Tashaun Gipson | D. Bush Deon Bush | |
| Free Safety | E. Jackson Eddie Jackson | S. McManis Sherrick McManis | — |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | P. O'Donnell Pat O'Donnell | — | — |
| Kicker | C. Santos Cairo Santos | E. Pineiro Eddy Pineiro | — |
| Long Snapper | P. Scales Patrick Scales | — | — |
| Holder | P. O'Donnell Pat O'Donnell | — | — |
| Punt Returner | T. Cohen Tarik Cohen | D. Mooney Darnell Mooney | |
| Kick Returner | C. Patterson Cordarrelle Patterson | D. Mooney Darnell Mooney |