Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | J. DanielsJayden Daniels | M. MariotaMarcus Mariota | |
| Running Back | R. WhiteRachaad White | A. EkelerAustin Ekeler | |
| Wide Receiver | S. DiggsStefon Diggs | A. WilliamsAntonio Williams | |
| Tight End | C. OkonkwoChigoziem Okonkwo | B. SinnottBen Sinnott | |
| Left Tackle | B. ColemanBrandon Coleman | A. WylieAndrew Wylie | |
| Left Guard | C. PaulChris Paul | L. PatrickLucas Patrick | |
| Center | L. PatrickLucas Patrick | N. AllegrettiNick Allegretti | |
| Right Guard | S. CosmiSamuel Cosmi | M. GulbinMatt Gulbin | |
| Right Tackle | J. Conerly Jr.Josh Conerly Jr. | A. WylieAndrew Wylie | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | C. OmenihuCharles Omenihu | J. NewtonJohnny Newton | — |
| Nose Tackle | T. SettleTim Settle | D. PayneDaron Payne | — |
| Right Defensive End | J. KinlawJavon Kinlaw | S. TuttleShy Tuttle | |
| Left Inside Linebacker | F. LuvuFrankie Luvu | J. MageeJordan Magee | — |
| Right Inside Linebacker | S. StylesSonny Styles | K. MedranoKain Medrano | |
| Strongside Linebacker | D. ArmstrongDorance Armstrong | K. ChaissonK'Lavon Chaisson | |
| Weakside Linebacker | O. OwehOdafe Oweh | J. JosephsJoshua Josephs | — |
| Right Cornerback | T. AmosTrey Amos | — | — |
| Left Cornerback | R. DouglasRasul Douglas | F. MoreauFabian Moreau | — |
| Slot Cornerback | A. RobertsonAmik Robertson | M. SainristilMike Sainristil | — |
| Strong Safety | N. CrossNick Cross | T. OwensTyler Owens | — |
| Free Safety | J. ReavesJeremy Reaves | Q. MartinQuan Martin |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | T. WayTress Way | — | — |
| Kicker | D. StevensDrew Stevens | — | — |
| Long Snapper | T. OttTyler Ott | — | — |
| Holder | T. WayTress Way | — | — |
| Punt Returner | A. WilliamsAntonio Williams | L. McCaffreyLuke McCaffrey | |
| Kick Returner | R. WhiteRachaad White | L. McCaffreyLuke McCaffrey |