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1:53Seahawks & 49ers Sound Off After NFC Clash
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2:29Week 18 Highlights: Seahawks at 49ers
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1:43Playoff Outlook for 49ers After Loss to Seahawks
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1:54Jonathan Jones: 'Seattle is Probably a Run-First Team'
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1:58How the Seattle Defense Was Effective in Limiting One of the Most Potent Offenses in the NFL
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1:5549ers One Win Away From Historic Home Playoff Run
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1:00Easiest Path: Win & Get The NFC 1-Seed
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9:39NFL Week 18 Game Preview: Seahawks at 49ers
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1:39NFL Week 18 Projections: Seahawks & 49ers Dueling for No. 1 Seed in NFC
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1:13NFL Week 18 Expert Pick: Seahawks or 49ers
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2:31NFL Week 18 Picks: Week 18 Parlay
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3:17NFL Week 18 Picks: Seahawks at 49ers
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2:59NFL Week 18 Picks: Seahawks at 49ers
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0:46Quick Look At Pete Prisco's NFL Power Rankings, Presented by Geico
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1:11Race for No.1 Seed In The NFC
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2:03Kyle Long Shares His Super Bowl Champion
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0:37Pick to win NFL Coach of the Year
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0:51Making The Case For Kyle Shanahan As Coach Of The Year
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1:5349ers, Seahawks Clash Week 18 To Decide NFC 1-Seed
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1:26Who Takes The NFC One Seed?
2025 Rushing
| STATS |
ATT
Rushing Attempts
|
YDS
Rushing Yards
|
AVG
Average Yards per Rush
|
TD
Rushing Touchdowns
|
LNG
Longest Rush
|
FL
Fumbles Lost
|
|---|---|---|---|---|---|---|
| Regular Season | — | — | — | — | — | — |
Top Isaac Guerendo News
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49ers' Isaac Guerendo: Healthy scratch again in Week 17
Guerendo (coach's decision) is inactive for Sunday night's contest against Chicago.
Guerendo will be a healthy scratch for the second straight week after having played in the team's previous 14 contests. Jordan James will get another nod as the 49ers' No. 3 running back behind Christian McCaffrey and Brian Robinson in Week 17.
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49ers' Isaac Guerendo: Inactive for MNF
Guerendo (coach's decision) is inactive for Monday night's game against the Colts.
Guerendo has appeared in all 14 games this season leading up to Monday night, but rookie Jordan James is getting the nod over him against the Colts as the Niners' RB3 behind Christian McCaffrey and Brian Robinson. All of Guerendo's 173 snaps this season have come on special teams.
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49ers' Isaac Guerendo: Role remains marginalized
Guerendo logged three snaps on special teams in Sunday's 37-24 win over the Titans.
Guerendo remained a non-factor on offense behind Christian McCaffrey and Brian Robinson on San Francisco's running back depth chart. The 25-year-old Guerendo once returned kickoffs for the 49ers, but the team has removed him from that role completely since Week 5. Barring a string of catastrophic injuries in the backfield, Guerendo can safely be ignored during the fantasy playoffs.
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49ers' Isaac Guerendo: No run on offense this season
Guerendo played all 10 of his snaps on special teams in Sunday's 26-15 loss to the Texans.
As a rookie last season, Guerendo showcased some explosiveness out of the San Francisco backfield with averages of 5.0 yards per carry and 10.1 yards per reception over 16 games, but he has yet to play a snap on offense in the 49ers' first eight games of 2025. With lead back Christian McCaffrey having thus far stayed healthy while handling huge snap and touch counts each week, Brian Robinson has picked up the remaining scraps left over in the backfield. So long as McCaffrey and Robinson are able to avoid injury, Guerendo looks as though he'll be limited to a role on kickoff returns and kick-coverage units.
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49ers' Isaac Guerendo: Returns one kickoff Thursday
Guerendo ran back one kickoff for 18 yards while receiving no carries or targets in Thursday's 26-23 overtime win over the Rams.
Christian McCaffrey continued to operate as San Francisco's bell cow (88 percent) while Brian Robinson (14 percent) remained the clear No. 2, which leaves Guerendo parked in the garage when the team is on offense. The 2024 fourth-round selection is stuck on special teams for the foreseeable future, needing an injury ahead of him on the depth chart to open up playing time. Guerendo generates no fantasy value in his current role when the 49ers visit the Buccaneers in Week 6.
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49ers' Isaac Guerendo: Logs 14 snaps on special teams
Guerendo logged 14 snaps on special teams and was not used on offense in Sunday's 26-21 loss to the Jaguars.
Guerendo couldn't even make an appearance in the box score as a return man after WR Skyy Moore handled all punt and kick returns Sunday. The 25-year-old Guerendo has logged zero snaps on offense through four games this season, leaving no room for fantasy utility as we encroach the quarter point of the season. Managers should have no concerns leaving Guerendo in the free-agent pool for Thursday's tilt against the Rams.
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49ers' Isaac Guerendo: Stuck on special teams
Guerendo did not receive a carry while gaining 19 yards on a kickoff return in Sunday's 16-15 win over the Cardinals.
Guerendo continued to be used exclusively on special teams, logging all 15 of his snaps there Sunday. Brian Robinson was the only running back to receive any carries outside of starter Christian McCaffrey. Guerendo carries no fantasy value heading into a Week 4 matchup against Jacksonville.
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49ers' Isaac Guerendo: No carries in Week 2 win
Guerendo returned two kickoffs for 47 yards and was not used on offense in Sunday's 26-21 win over the Saints.
Guerendo failed to see the field on offense Sunday, logging all 17 of his snaps on special teams. Veteran backup Brian Robinson continues to handle all of the touches starter Christian McCaffrey doesn't gobble up on game days. More of the same can be expected against the Cardinals in Week 3, leaving Guerendo off the fantasy radar until an injury opens up playing time for the sophomore.
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Player Bio
| HT/WT: 6-0, 221 lbs |
| Birthplace: Clayton, IN |
| Age: 25 |
| School: Louisville |
| Experience: 2 |


















