Regular Season
| Date | OPP | Time / TV | Venue | Home Starter | Away Starter | Buy Tickets |
|---|---|---|---|---|---|---|
| Mar 31, 2022 | vs | Citi Field | — | — | — | |
| Apr 2, 2022 | vs | Citi Field | — | — | — | |
| Apr 3, 2022 | vs | Citi Field | — | — | — | |
| Apr 4, 2022 | vs | Citi Field | — | — | — | |
| Apr 5, 2022 | vs | Citi Field | — | — | — | |
| Apr 7, 2022 | @ | Nationals Park | — | — | — | |
| Apr 8, 2022 | @ | Nationals Park | — | — | — | |
| Apr 9, 2022 | @ | Nationals Park | — | — | — | |
| Apr 10, 2022 | @ | Nationals Park | — | — | — | |
| Apr 11, 2022 | @ | Citizens Bank Park | — | — | — | |
| Apr 12, 2022 | @ | Citizens Bank Park | — | — | — | |
| Apr 13, 2022 | @ | Citizens Bank Park | — | — | — | |
| Apr 15, 2022 | vs | Citi Field | — | — | — | |
| Apr 16, 2022 | vs | Citi Field | — | — | — | |
| Apr 17, 2022 | vs | Citi Field | — | — | — | |
| Apr 18, 2022 | vs | Citi Field | — | — | — | |
| Apr 19, 2022 | vs | Citi Field | — | — | — | |
| Apr 20, 2022 | vs | Citi Field | — | — | — | |
| Apr 21, 2022 | vs | Citi Field | — | — | — | |
| Apr 22, 2022 | @ | Chase Field | — | — | — | |
| Apr 23, 2022 | @ | Chase Field | — | — | — | |
| Apr 24, 2022 | @ | Chase Field | — | — | — | |
| Apr 25, 2022 | @ | Busch Stadium | — | — | — | |
| Apr 26, 2022 | @ | Busch Stadium | — | — | — | |
| Apr 27, 2022 | @ | Busch Stadium | — | — | — | |
| Apr 29, 2022 | vs | Citi Field | — | — | — | |
| Apr 30, 2022 | vs | Citi Field | — | — | — | |
| May 1, 2022 | vs | Citi Field | — | — | — | |
| May 2, 2022 | vs | Citi Field | — | — | — | |
| May 3, 2022 | vs | Citi Field | — | — | — | |
| May 4, 2022 | vs | Citi Field | — | — | — | |
| May 5, 2022 | @ | Citizens Bank Park | — | — | — | |
| May 6, 2022 | @ | Citizens Bank Park | — | — | — | |
| May 7, 2022 | @ | Citizens Bank Park | — | — | — | |
| May 8, 2022 | @ | Citizens Bank Park | — | — | — | |
| May 10, 2022 | @ | Nationals Park | — | — | — | |
| May 11, 2022 | @ | Nationals Park | — | — | — | |
| May 12, 2022 | @ | Nationals Park | — | — | — | |
| May 13, 2022 | vs | Citi Field | — | — | — | |
| May 14, 2022 | vs | Citi Field | — | — | — | |
| May 15, 2022 | vs | Citi Field | — | — | — | |
| May 16, 2022 | vs | Citi Field | — | — | — | |
| May 17, 2022 | vs | Citi Field | — | — | — | |
| May 18, 2022 | vs | Citi Field | — | — | — | |
| May 19, 2022 | vs | Citi Field | — | — | — | |
| May 20, 2022 | @ | Coors Field | — | — | — | |
| May 21, 2022 | @ | Coors Field | — | — | — | |
| May 22, 2022 | @ | Coors Field | — | — | — | |
| May 23, 2022 | @ | Oracle Park | — | — | — | |
| May 24, 2022 | @ | Oracle Park | — | — | — | |
| May 25, 2022 | @ | Oracle Park | — | — | — | |
| May 27, 2022 | vs | Citi Field | — | — | — | |
| May 28, 2022 | vs | 7:15 pm
FOX
| Citi Field | — | — | — |
| May 29, 2022 | vs | Citi Field | — | — | — | |
| May 30, 2022 | vs | Citi Field | — | — | — | |
| May 31, 2022 | vs | Citi Field | — | — | — | |
| Jun 1, 2022 | vs | Citi Field | — | — | — | |
| Jun 2, 2022 | @ | Dodger Stadium | — | — | — | |
| Jun 3, 2022 | @ | Dodger Stadium | — | — | — | |
| Jun 4, 2022 | @ | Dodger Stadium | — | — | — | |
| Jun 5, 2022 | @ | Dodger Stadium | — | — | — | |
| Jun 6, 2022 | @ | Petco Park | — | — | — | |
| Jun 7, 2022 | @ | Petco Park | — | — | — | |
| Jun 8, 2022 | @ | Petco Park | — | — | — | |
| Jun 10, 2022 | @ | Angel Stadium of Anaheim | — | — | — | |
| Jun 11, 2022 | @ | Angel Stadium of Anaheim | — | — | — | |
| Jun 12, 2022 | @ | Angel Stadium of Anaheim | — | — | — | |
| Jun 14, 2022 | vs | Citi Field | — | — | — | |
| Jun 15, 2022 | vs | Citi Field | — | — | — | |
| Jun 16, 2022 | vs | Citi Field | — | — | — | |
| Jun 17, 2022 | vs | Citi Field | — | — | — | |
| Jun 18, 2022 | vs | Citi Field | — | — | — | |
| Jun 19, 2022 | vs | Citi Field | — | — | — | |
| Jun 20, 2022 | vs | Citi Field | — | — | — | |
| Jun 21, 2022 | @ | Minute Maid Park | — | — | — | |
| Jun 22, 2022 | @ | Minute Maid Park | — | — | — | |
| Jun 24, 2022 | @ | loanDepot park | — | — | — | |
| Jun 25, 2022 | @ | loanDepot park | — | — | — | |
| Jun 26, 2022 | @ | loanDepot park | — | — | — | |
| Jun 28, 2022 | vs | Citi Field | — | — | — | |
| Jun 29, 2022 | vs | Citi Field | — | — | — | |
| Jul 1, 2022 | vs | Citi Field | — | — | — | |
| Jul 2, 2022 | vs | Citi Field | — | — | — | |
| Jul 3, 2022 | vs | Citi Field | — | — | — | |
| Jul 4, 2022 | @ | Great American Ball Park | — | — | — | |
| Jul 5, 2022 | @ | Great American Ball Park | — | — | — | |
| Jul 6, 2022 | @ | Great American Ball Park | — | — | — | |
| Jul 7, 2022 | vs | Citi Field | — | — | — | |
| Jul 8, 2022 | vs | Citi Field | — | — | — | |
| Jul 9, 2022 | vs | Citi Field | — | — | — | |
| Jul 10, 2022 | vs | Citi Field | — | — | — | |
| Jul 11, 2022 | @ | Truist Park | — | — | — | |
| Jul 12, 2022 | @ | Truist Park | — | — | — | |
| Jul 13, 2022 | @ | Truist Park | — | — | — | |
| Jul 14, 2022 | @ | Wrigley Field | — | — | — | |
| Jul 15, 2022 | @ | Wrigley Field | — | — | — | |
| Jul 16, 2022 | @ | Wrigley Field | — | — | — | |
| Jul 17, 2022 | @ | Wrigley Field | — | — | — | |
| Jul 22, 2022 | vs | Citi Field | — | — | — | |
| Jul 23, 2022 | vs | Citi Field | — | — | — | |
| Jul 24, 2022 | vs | Citi Field | — | — | — | |
| Jul 26, 2022 | vs | Citi Field | — | — | — | |
| Jul 27, 2022 | vs | Citi Field | — | — | — | |
| Jul 29, 2022 | @ | loanDepot park | — | — | — | |
| Jul 30, 2022 | @ | loanDepot park | — | — | — | |
| Jul 31, 2022 | @ | loanDepot park | — | — | — | |
| Aug 1, 2022 | @ | Nationals Park | — | — | — | |
| Aug 2, 2022 | @ | Nationals Park | — | — | — | |
| Aug 3, 2022 | @ | Nationals Park | — | — | — | |
| Aug 4, 2022 | vs | Citi Field | — | — | — | |
| Aug 5, 2022 | vs | Citi Field | — | — | — | |
| Aug 6, 2022 | vs | Citi Field | — | — | — | |
| Aug 7, 2022 | vs | Citi Field | — | — | — | |
| Aug 8, 2022 | vs | Citi Field | — | — | — | |
| Aug 9, 2022 | vs | Citi Field | — | — | — | |
| Aug 10, 2022 | vs | Citi Field | — | — | — | |
| Aug 12, 2022 | vs | Citi Field | — | — | — | |
| Aug 13, 2022 | vs | Citi Field | — | — | — | |
| Aug 14, 2022 | vs | Citi Field | — | — | — | |
| Aug 15, 2022 | @ | Truist Park | — | — | — | |
| Aug 16, 2022 | @ | Truist Park | — | — | — | |
| Aug 17, 2022 | @ | Truist Park | — | — | — | |
| Aug 18, 2022 | @ | Truist Park | — | — | — | |
| Aug 19, 2022 | @ | Citizens Bank Park | — | — | — | |
| Aug 20, 2022 | @ | 7:15 pm
FOX
| Citizens Bank Park | — | — | — |
| Aug 21, 2022 | @ | Citizens Bank Park | — | — | — | |
| Aug 22, 2022 | @ | Yankee Stadium | — | — | — | |
| Aug 23, 2022 | @ | Yankee Stadium | — | — | — | |
| Aug 25, 2022 | vs | Citi Field | — | — | — | |
| Aug 26, 2022 | vs | Citi Field | — | — | — | |
| Aug 27, 2022 | vs | Citi Field | — | — | — | |
| Aug 28, 2022 | vs | Citi Field | — | — | — | |
| Aug 30, 2022 | vs | Citi Field | — | — | — | |
| Aug 31, 2022 | vs | Citi Field | — | — | — | |
| Sep 1, 2022 | vs | Citi Field | — | — | — | |
| Sep 2, 2022 | vs | Citi Field | — | — | — | |
| Sep 3, 2022 | vs | 7:15 pm
FOX
| Citi Field | — | — | — |
| Sep 4, 2022 | vs | Citi Field | — | — | — | |
| Sep 5, 2022 | @ | PNC Park | — | — | — | |
| Sep 6, 2022 | @ | PNC Park | — | — | — | |
| Sep 7, 2022 | @ | PNC Park | — | — | — | |
| Sep 9, 2022 | @ | loanDepot park | — | — | — | |
| Sep 10, 2022 | @ | loanDepot park | — | — | — | |
| Sep 11, 2022 | @ | loanDepot park | — | — | — | |
| Sep 12, 2022 | vs | Citi Field | — | — | — | |
| Sep 13, 2022 | vs | Citi Field | — | — | — | |
| Sep 14, 2022 | vs | Citi Field | — | — | — | |
| Sep 15, 2022 | vs | Citi Field | — | — | — | |
| Sep 16, 2022 | vs | Citi Field | — | — | — | |
| Sep 17, 2022 | vs | Citi Field | — | — | — | |
| Sep 18, 2022 | vs | Citi Field | — | — | — | |
| Sep 19, 2022 | @ | American Family Field | — | — | — | |
| Sep 20, 2022 | @ | American Family Field | — | — | — | |
| Sep 21, 2022 | @ | American Family Field | — | — | — | |
| Sep 23, 2022 | @ | Oakland-Alameda County Coliseum | — | — | — | |
| Sep 24, 2022 | @ | Oakland-Alameda County Coliseum | — | — | — | |
| Sep 25, 2022 | @ | Oakland-Alameda County Coliseum | — | — | — | |
| Sep 27, 2022 | vs | Citi Field | — | — | — | |
| Sep 28, 2022 | vs | Citi Field | — | — | — | |
| Sep 30, 2022 | @ | Truist Park | — | — | — | |
| Oct 1, 2022 | @ | Truist Park | — | — | — | |
| Oct 2, 2022 | @ | Truist Park | — | — | — |
